Phys.org

Virtual library of 1 million new macrolide scaffolds could help speed drug discovery

Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library—called V1M—contains chemical structures and computed ...
News Medical

Researchers create largest publicly available virtual library of macrolide scaffolds

Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library - called V1M - contains chemical structures and ...
Phys.org

Study sheds light on the function of a key antibiotic-producing enzyme

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...
Nature

Isolation and characterization of 23-O-mycinosyl-20-dihydro-rosamicin: a new rosamicin analogue derived from engineered Micromonospora rosaria

Macrolides, including some of the most important antibiotics clinically used, contain deoxysugars attached to an aglycone core. These sugars often impart specific biological activity to the molecule ...
News Medical

Analyzing bacterial enzymes in pikromycin synthesis

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...
technologynetworks

Virtual Library of 1 Million New Macrolide Scaffolds Helps Speed Drug Discovery

Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library - called V1M - contains chemical structures and ...